Escaping the Valley of Death
نویسندگان
چکیده
منابع مشابه
Escaping death to quiescence
Cancer recurrence is associated with treatment failure and is the main cause of death, 1 and thus remains to be a major clinical challenge. elevated level of the cyclin-dependent kinase 1 (CDK1) correlates with cancer recurrence and treatment resistance in patients with breast cancer or colorectal cancer. 2,3 it is proposed that defects in CDKs may lead to the accumulated genetic defects, which...
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Translating the knowledge from biomedical science into clinical applications that help patients has been compared to crossing a valley of death because of the many issues that separate the bench from the bedside and threaten to stall progress. But translation is also inhibited by a science policy environment with its own impediments. Mapping these policy impediments give a more complete picture...
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ژورنال
عنوان ژورنال: Molecular Therapy
سال: 2012
ISSN: 1525-0016
DOI: 10.1038/mt.2012.21